Hear from our 2018 SIG Meeting travel grant beneficiaries
For each of our BioExcel training events we make a limited number of travel bursaries available. We ask the beneficiaries of the BioExcel
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AuthorMichelle Mendonca
Large-scale prediction of binding affinity in protein-small ligand complexes: the PRODIGY-LIG web server.
Abstract Recently we published PROtein binDIng enerGY (PRODIGY), a web-server for the prediction of binding affinity in protein–protein complexes. By using a combination
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Protein-ligand pose and affinity prediction. Lessons from D3R Grand Challenge 3.
Abstract We report the performance of HADDOCK in the 2018 iteration of the Grand Challenge organised by the D3R consortium. Building on the
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Targeting RNA structure in SMNS reverses spinal muscular atrophy molecular phenotypes.
This paper was published in Nature Communications in May 2018. Abstract Modification of SMN2 exon 7 (E7) splicing is a validated therapeutic strategy against spinal
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Protein Flexibility and Synergy of HMG Domains Underlie U-Turn Bending of DNA by TFAM in Solution.
This paper was published in the Biophysical Journal in May 2018. Abstract Human mitochondrial transcription factor A (TFAM) distorts DNA into a U-turn,
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Defining distance restraints in HADDOCK
Abstract In a recent issue of Nature Protocols, Orbán-Németh et al.1 present a protocol to predict structural models of proteins and their complexes
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